Agent Name

1-Nitropyrene

CAS Number

5522-43-0

Formula

C16-H9-N-O2

Major Category

Other Classes

Synonyms

3-Nitropyrene; Pyrene, 1-nitro-; [ChemIDplus]

Category

Polycyclic Aromatic Hydrocarbons

Description

Yellow solid; [HSDB] Gold solid; [MSDSonline]

Sources/Uses

Found in particulates in emissions from combustion, e.g., diesel exhausts; Used as a research chemical and produced by one company as an intermediate for 1-azidopyrene, used in photosenistive printing; [NTP]

Comments

"1-Nitropyrene is the 'marker' nitroPAH for diesel exhaust, and its presence in ambient air samples is a sign of pollution by diesel vehicle traffic. . . . In general, the mass emission of particles, emissions of particle-bound PAHs and nitroPAHs, and mutagenic activity levels generally decreased with the use of either particulate traps or catalytic converters." [Reference #1] "Whether the nitroarenes are responsible for, or contribute to, the human carcinogenicity of diesel exhaust has not been determined." [NTP] May cause irritation; [MSDSonline] See "POLYCYCLIC AROMATIC HYDROCARBONS."

Reference Link

Selected NItro- and Nitro-Oxy-Polycyclic Aromatic Hydrocarbons

Exposure Assessment
Vapor Pressure

5.52E-8 mm Hg

Reference Link

NTP Report on Carcinogens, 12th Edition: Nitroarenes (Selected)

Adverse Effects
IARC Carcinogen

Probable Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.