Agent Name

2,2',4,4',5,5'-Hexachlorobiphenyl

CAS Number

35065-27-1

Formula

C12-H4-Cl6

Major Category

Other Classes

Synonyms

1,1'-Biphenyl, 2,2',4,4',5,5'-hexachloro-; 2,2',4,4',5,5'-Hexachloro-1,1'-biphenyl; 2,4,5,2',4',5'-Hexachlorobiphenyl; Biphenyl, 2,2',4,4',5,5'-hexachloro-; CB-153; HCBP; K 153; PCB 153; [ChemIDplus] UN3432

Category

Halogenated Polyaromatics

Description

Solid; [MSDSonline]

Sources/Uses

Found in various Aroclor products; [HSDB]

Comments

Emergency medical treatment: see PCB-PBB; A skin and eye irritant; Gross and histopathological changes to the liver and some evidence of reproductive toxicity (more resorptions and abnormal placentas) were observed in high dose animal studies; [HSDB] See "Chlorodiphenyl (42% chlorine)." For IARC changes in 2016, see "Polychlorinated biphenyls" and the linked occupational disease.

Restricted

PCB's not commercially produced in the US since 1977; [HSDB]

Exposure Assessment
Vapor Pressure

3.43E-6 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Polychlorinated biphenyls, solid"

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Dermatotoxin

Chloracne

IARC Carcinogen

Known Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: