Agent Name

2,2-Dibromo-3-nitrilopropionamide

CAS Number

10222-01-2

Formula

C3-H2-Br2-N2-O

Major Category

Other Uses

Synonyms

2,2-Dibromo-2-carbamoylacetonitrile; 2,2-Dibromo-2-cyanoacetamide; DPNPA; Dibromocyanoacetamide; XD 7287L; XD-1603; XD-7287l Antimicrobial; Acetamide, 2,2-dibromo-2-cyano-; Acetamide, 2-cyano-2,2-dibromo-; [ChemIDplus]

Category

Biocides/Disinfectants

Description

White solid; [HSDB] Colorless to yellow liquid with a moldy pungent odor; [CAMEO] White powder; [MSDSonline]

Sources/Uses

Used as an algicide, bactericide, and fungicide; as a preservative in pulp, paper, and paperboard mill water systems and industrial water cooling systems; as a preservative in animal glues, metalworking cutting fluids, oil recovery drilling muds, emulsions, paints, and paper products; [HSDB]

Comments

Poisonous by ingestion or IV route; A strong skin and eye irritant; Emits bromine and nitrogen oxides when heated; [Sax] Several human incidents reported to EPA after spills or misuse: eye, nose, throat, and respiratory tract irritation; [HSDB] DBNPA is a skin sensitizer; It is teratogenic in rabbits; It may cause eye and respiratory tract irritation; [EPA REDs] Danger of skin sensitization; [MAK] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; May cause skin sensitization; [MSDSonline]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

0.0009 mm Hg

Lethal Concentration

LC50 (rat) = 320 mg/m3/4h

Adverse Effects
Skin Sensitizer

Yes

Toxic Pneumonitis

Yes

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: