Agent Name

2,3,4,6-Tetrachlorophenol

CAS Number

58-90-2

Formula

C6-H2-Cl4-O

Major Category

Other Classes

Synonyms

1-Hydroxy-2,3,4,6-tetrachlorobenzene; 2,4,5,6-Tetrachlorophenol; Chlorophenols; Dowicide 6; Phenol, 2,3,4,6-tetrachloro-; [ChemIDplus] UN2020

Category

Chlorophenols

Description

Brown solid; [Hawley]

Sources/Uses

Used as a pesticide and fungicide; as a slimicide for paper mills; as a preservative; as a component in pentachlorophenol wood preservative; Discontinued by the DOW Chemical Co.; No longer commercially produced in the US; Pure 2,3,4,6-tetrachlorophenol is not sold commercially because of the difficulty encountered in adjusting the chlorination at the tetra stage. It is found in combination with pentachlorophenol. [HSDB]

Comments

A nose, throat, and respiratory tract irritant; [HSDB] Prolonged contact corrosive to eyes; May cause skin burns, hyperthermia, methemoglobinemia, liver and kidney damage, and convulsions; [CAMEO] A skin, eye, and respiratory tract irritant; May cause liver injury and chloracne; [ICSC] A severe skin and eye irritant; A mucous membrane and upper respiratory tract irritant; May cause liver damage; Effects in high-dose animal studies include convulsions or effect on seizure threshold; [MSDSonline] See "CHLOROPHENOLS."

Exposure Assessment
Vapor Pressure

0.00423 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Chlorophenols, solid."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Other Poison

Uncoupler

Dermatotoxin

Chloracne

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: