Agent Name

ANTU

Alternative Name

alpha-Naphthyl thiourea

CAS Number

86-88-4

Formula

C11-H10-N2-S

Major Category

Pesticides

Synonyms

alpha-Naphthyl thiocarbamide; 1-Naphthyl thiourea; alpha-Naphthyl thiourea

Category

Rodenticides

Description

White crystalline or gray, odorless powder. [rodenticide]

Comments

The lethal oral dose in humans is about 4 g/kg; TLV based on thyroid effects and nausea; In high-dose feeding and intraperitoneal injection studies, animals develop liver injury, pleural and pericardial effusions, and pulmonary edema. [ACGIH]

Restricted

No ANTU products are registered in the USA. [LaDou, 4th Ed., p. 564]

Reference Link

NIOSH Occupational Health Guidelines for Chemical Hazards: ANTU

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.3 mg/m3

PEL (OSHA)

0.3 mg/m3

IDLH (NIOSH)

100 mg/m3

Excerpts from Documentation for IDLHs

Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ANTU. However, based on acute oral toxicity data in humans [Stolman 1969] and animals [Gosselin et al. 1984; Perkow 1971/76], the original IDLH for ANTU (100 mg/m3) is not being revised at this time.

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: