Agent Name

2,4-Dichlorophenol

CAS Number

120-83-2

Formula

C6-H4-Cl2-O

Major Category

Other Classes

Synonyms

1-Hydroxy-2,4-dichlorobenzene; 2,4-DCP; 2,4-Dichlorohydroxybenzene; 4,6-Dichlorophenol; Phenol, 2,4-dichloro-; [ChemIDplus] UN2020

Category

Chlorophenols

Description

Colorless to pale yellow solid with a strong medicinal odor; Melts at 45 deg C; [HSDB] Crystalline solid; mp = 65-68 deg C; [MSDSonline]

Sources/Uses

Used to make herbicides, dyestuffs, mothproofing agents, antiseptics, seed disinfectants, miticides, wood preservatives, and the antihelminthic bithionol sulfoxide; According to a 1982 report, it was being used in the following industries: wood treatment, tanneries, textile plants, pulp and paper mills, and pesticide services; [HSDB]

Comments

A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; "Exposure to small amounts of the molten or liquid form of the substance may result in extensive skin absorption and rapid death." [ICSC] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; May be absorbed through skin; Effects in high-dose animal studies include acute tubular necrosis and convulsions; [MSDSonline] The mechanism of toxicity is uncoupling oxidative phosphorylation; Lethal dose is approximately 21 grams or a skin splash of 15 ml of molten 2,4-DCP; [AIHA] See "CHLOROPHENOLS."

Exposure Assessment
WEEL

1 ppm

Vapor Pressure

0.11 mm Hg

Explanatory Notes

Flash point = 113 deg C; [Hawley] The Guide in the Emergency Response Guidebook is for "Chlorophenols, solid."

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Nephrotoxin

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Uncoupler

Dermatotoxin

Skin Burns

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: