Agent Name

Benomyl

CAS Number

17804-35-2

Formula

C14-H18-N4-O3

Major Category

Pesticides

Synonyms

1-(Butylcarbamoyl)-2-benzimidazol-methylcarbamat [German]; 1-(Butylcarbamoyl)-2-benzimidazolecarbamic acid, methyl estter; 1-(N-Butylcarbamoyl)-2-(methoxy-carboxamido)-benzimidazol [German]; Agrocit; Arbortrine; Arilate; BBC; BC 6597; BNM; Benlate; Benlate 50; Benlate 50 W; Benomyl; Benomyl 50W; Benomyl-Imex; Chinoin-fundazol; D 1991; Du Pont 1991; Dupont 1991; F 1991; F1991; Fundazol; Fungicide D-1991; Fungochrom; Kribenomyl; MBC; Methyl 1-(butylamino)carbonyl-1H-benzimidazol-2-ylcarbamate; Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate; Methyl 1-(butylcarbamoyl)-2-benzimidazolylcarbamate; Methyl N-(1-butylcarbamoyl-2-benzimidazole)carbamate; NS 02; NS 02 (fungicide); Tersan 1991; Uzgen; [ChemIDplus]

Category

Fungicides

Description

White crystalline solid with a faint, acrid odor. [fungicide] [Note: Decomposes without melting above 572 degrees F.]; [NIOSH]

Sources/Uses

A systemic fungicide with inhibitory effects on mites used on apples, soybeans, celery, beans, sugarcane, peanuts, nuts, citrus, grapes, mushrooms, berries, tomatoes, mangoes, avocados, vegetable crop seeds, rice, bulbs, grasses, shade trees, and other crops; In addition to a fungicide, has also been used in the manufacturing of textiles and paint pigments, as an oxidizing agent in sewage treatment, and as a drug (veterinarian antihelminthic); [ACGIH]

Comments

It is classified as "practically nontoxic"; [EXTOXNET] Allergic contact dermatitis in agricultural workers; [Marks] In high-dose reproductive studies of animals, benomyl causes testicular damage, fetal losses, and birth defects. [Frazier, p. 234-6] "Substances that have been shown to induce genetic damage in germ cells of humans or animals, or which produce mutagenic effects in somatic cells and have been shown to reach the germ cells in their active forms." [MAK] A dermal sensitizer; TLV Basis: Upper respiratory tract irritation; male reproductive system, testicular, and embryo/fetal damage; [ACGIH] A weak skin sensitizer; [Kanerva, p. 1754]

Reference Link

EXTOXNET PIP - BENOMYL

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

1 mg/m3, inhalable particulate matter

PEL (OSHA)

15 mg/m3(total dust), 5 mg/m3(respirable fraction)

Vapor Pressure

3.7E-9 mm Hg

Reference Link

ICSC: Benomyl

Adverse Effects
Skin Sensitizer

Yes

Reproductive Toxin

Yes

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: