Agent Name

2,5-Dimethylphenol

Alternative Name

2,5-Xylenol

CAS Number

95-87-4

Formula

C8-H10-O

Major Category

Other Classes

Synonyms

2,5-Xylenol; 1,2,5-Xylenol; 1,4-Dimethyl-2-hydroxybenzene; 1-Hydroxy-2,5-dimethylbenzene; 2,5-DMP; 3,6-Dimethylphenol; 3,6-Xylenol; 6-Methyl-m-cresol; Phenol, 2,5-dimethyl-; p-Xylenol; [ChemIDplus] UN2261

Category

Phenols

Description

Colorless to off-white solid; [CAMEO] Needles; [MSDSonline]

Sources/Uses

Used to make phenolic resins and (in isomeric mixtures) as an antioxidant for lubricating oils, gasoline, and elastomers; [HSDB]

Comments

Causes ataxia and convulsions in lethal-dose feeding studies; [RTECS] Corrosive to tissues; Inhalation may cause laryngeal spasm, edema of the bronchi, and chemical pneumonitis; May induce methemoglobinemia; Chronic exposure may cause liver and kidney damage; [CAMEO] Safe when used as a flavoring agent in food; [JECFA] Toxic by ingestion and skin contact; May cause burns; [eChemPortal: ESIS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; May be absorbed through skin; [MSDSonline] See "Phenol."

Exposure Assessment
Vapor Pressure

0.15 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Xylenols, solid." See "2018 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: