Agent Name

2,5-Dinitrophenol

CAS Number

329-71-5

Formula

C6-H4-N2-O5

Major Category

Nitrogen Compounds

Synonyms

2,5-DNP; 2,5-Dinitrofenol [Czech]; Phenol, 2,5-dinitro-; Phenol, gamma-dinitro-; gamma-Dinitrophenol; [ChemIDplus] UN1320; UN0076

Category

Nitrophenols

Description

Yellow solid; [Merck Index] Light yellow crystals; [MSDSonline]

Sources/Uses

Used as an indicator and to make dyes and other organic chemicals; [Merck Index]

Comments

Causes first degree burns after brief exposure; [CHRIS] Emergency treatment: see "Dinitrophenol." A mucous membrane irritant; Can induce methemoglobinemia; [HSDB] Toxic by inhalation, ingestion, and skin contact; [eChemPortal: ESIS] An irritant; Readily absorbed through skin; May cause liver damage; Disrupts oxidative phosphorylation; [MSDSonline] See "Dinitrophenol."

Exposure Assessment
Vapor Pressure

0.000122 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Dinitrophenol, wetted with not less than 15% water, by weight".

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Other Poison

Uncoupler

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: