Agent Name

Benzyl chloride

CAS Number

100-44-7

Formula

C7-H7-Cl

Major Category

Other Classes

Synonyms

Benzene, (chloromethyl)-; Benzile (cloruro di) [Italian]; Benzyl chloride; Benzylchlorid [German]; Benzylchloride; Benzyle (chlorure de) [French]; Chloromethylbenzene; Chlorophenylmethane; Chlorure de benzyle [French]; Toluene, alpha-chloro-; Tolyl chloride; alpha-Chlorotoluene; alpha-Chlortoluol [German; [ChemIDplus] UN1738

Category

Halogenated Monoaromatics

Description

Colorless to slightly yellow liquid with a pungent, aromatic odor; [NIOSH]

Sources/Uses

Used in the manufacture of dyes, plasticizers, lubricants, pharmaceuticals, and other organic chemicals; [ACGIH]

Comments

A mucous membrane and respiratory irritant; [ACGIH] A lachrymator; [CHEMINFO] Corrosive to the eyes; Irritating to the respiratory tract and may cause pulmonary edema; May damage the liver and kidneys and cause CNS depression; [ICSC]

Reference Link

NIOSH Occupational Health Guidelines for Chemical Hazards: Benzyl chloride

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

1 ppm

PEL (OSHA)

1 ppm

IDLH (NIOSH)

10 ppm

Excerpts from Documentation for IDLHs

Human data: It has been reported that an exposure to 16 ppm for 1 minute is intolerable [Flury and Zernik 1931]. It has also been reported that 10 to 19 ppm immediately causes weeping and twitching of the eyelids [ILO 1971].

Vapor Pressure

1.23 mm Hg

Odor Threshold Low

0.04 ppm

Odor Threshold High

0.04 ppm

RD50

17 ppm

Lethal Concentration

LC50 (rat) = 150 ppm/2H

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.041 ppm); Flash point = 153 deg F;

Half Life

Whole body (animal studies): 2-3 days; [TDR, p. 177]

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Probable Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.