Agent Name

2-Amino-4-nitrophenol

CAS Number

99-57-0

Formula

C6-H6-N2-O3

Major Category

Nitrogen Compounds

Synonyms

1-Amino-2-hydroxy-5-nitrobenzene; 1-Hydroxy-2-amino-4-nitrobenzene; 1-Nitro-3-amino-4-hydroxybenzene; 2-Amino-4-nitrofenol [Czech]; 2-Hydroxy-5-nitroaniline; 3-Amino-4-hydroxynitrobenzene; 4-Nitro-2-aminofenol [Czech]; 4-Nitro-2-aminophenol; C.I. 76530; CI 76530; Phenol, 2-amino-4-nitro-; Rodol 42; p-Nitro-o-aminophenol; p-Nitroaminofenol [Polish]; [ChemIDplus]

Category

Nitrophenols

Description

Yellow-brown or orange solid; [HSDB] Gold colored powder; [MSDSonline]

Sources/Uses

Used as a intermediate for mordant and acid dyes; as a component of hair dyes; as an antioxidant and light stabilizer in butyl rubbers; and as a catalyst in the manufacture of hexadiene; [HSDB]

Comments

Moderate irritant in rabbit eye; Causes somnolence and ataxia in lethal-dose studies of rats; Causes renal tubular changes in 13 week feeding studies of rats; A tumorigen and mutagen; [RTECS] A skin, eye, and respiratory tract irritant; [CAMEO]

Exposure Assessment
Vapor Pressure

3.52E-5 mm Hg

Explanatory Notes

Flash point = 100 deg C; [CHEMINFO]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: