Agent Name

2-Aminoanthraquinone

CAS Number

117-79-3

Formula

C14-H9-N-O2

Major Category

Dyes

Synonyms

2-Amino-9,10-anthracenedione; 2-Amino-9,10-anthraquinone; 9,10-Anthracenedione, 2-amino-; Aminoanthraquinone; beta-Anthraquinonylamine; [ChemIDplus]

Category

Anthraquinone Dyes

Description

Red or orange-brown solid; [HSDB] Orange-brown powder; [MSDSonline]

Sources/Uses

Used as an intermediate for dyes and pharmaceuticals; [HSDB]

Comments

No listed effects of short-term or long-term exposure; [ICSC] Evidence for carcinogenicity (hepatocellular neoplasms and carcinomas) in rats and mice; Effects to female rats in sub-chronic and chronic feeding studies include nephrotoxicity and decreased hemoglobin; Emergency treatment: "Anthraquinones"; Anthraquinones have cathartic action after ingestion, and in severe cases, may cause kidney damage, liver enzyme elevation, GI hemorrhage, seizures, and coma; [HSDB] May cause irritation and be absorbed through skin; Carcinogenic to animals; [CAMEO] Not irritating to skin or eyes of rabbits; Evidence for mutagenicity includes positive results in six of seven Ames Tests using various strains of Salmonella typhimurium, two cytogenic assays, four mouse lymphoma assays, and three in-vitro micronucleus assays; [IUCLID]

Exposure Assessment
Vapor Pressure

5.0E-11 mm Hg

Explanatory Notes

Flash point = 283 deg C; [ICSC]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.