Agent Name

2-Chloro-1,1,1,2-tetrafluoroethane

CAS Number

2837-89-0

Formula

C2-H-Cl-F4

Major Category

Solvents

Synonyms

1,1,1,2-Tetrafluoro-2-chloroethane; 1,1,1,2-Tetrafluorochloroethane; 1-Chloro-1,2,2,2-tetrafluoroethane; Freon 124; HCFC 124; Hfa-124; R 124; Ethane, 2-chloro-1,1,1,2-tetrafluoro-; Chlorotetrafluoroethane; [ChemIDplus] UN1021

Category

Chlorofluorocarbons

Description

A colorless gas with a faint ethereal odor at room temperature and atmospheric pressure; Colorless liquid under pressurized conditions; [eChemPortal: SIDSUNEP] Colorless volatile liquid; Faint sweetish odor; Gas at ambient temperatures; [MSDSonline]

Sources/Uses

Used as a foam blowing agent and refrigerant; [eChemPortal: SIDSUNEP]

Comments

Evaporating liquid can cause frostbite; [CHEMINFO] Can cause anesthesia and sensitize the heart to catecholamines; May cause liver injury; Vapors are heavier than air and can accumulate in low-lying areas; [HSDB] In confined space spill, may displace air and act as simple asphyxiant; Evaporating liquid can cause frostbite; Inhalation of high concentrations can cause CNS depression and cardiac arrhythmias; A severe eye irritant; [MSDSonline] 25,000 ppm is the threshold for cardiac sensitization in dogs; [AIHA]

Exposure Assessment
WEEL

1000 ppm

Lethal Concentration

LC50 (rat) > 360,000 ppm/6H;

Explanatory Notes

Boiling point = -12 deg C; [HSDB]

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Simple Asphyxiant

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: