Agent Name

2-Chlorophenol

CAS Number

95-57-8

Formula

C6-H5-Cl-O

Major Category

Other Classes

Synonyms

2-Chloro-1-hydroxybenzene; 2-Hydroxychlorobenzene; o-Chlorophenic acid; o-Chlorophenol; o-Chlorphenol [German]; p-Chlorfenol [Czech]; Pine-O Disinfectant; Septi-Kleen; Phenol, 2-chloro-; Phenol, o-chloro-; [ChemIDplus] CHLORO-2 PHENOL; OCP; Ortho chlorophenol; ORTHOMONOCHLOROPHENOL; [IUCLID] UN2021

Category

Chlorophenols

Description

Colorless to yellow-brown liquid with an unpleasant odor; [Hawley] Sensitive to light and moisture; [CHEMINFO] Faintly yellow clear liquid with a stench; [Sigma-Aldrich MSDS]

Sources/Uses

Used in the production of higher chlorinated phenols, catechol, profenofos, dyestuffs, and preservatives; Also used to extract sulfur and nitrogen compounds from coal and as a soil sterilant, disinfectant, antiseptic, and phenolic resin comonomer; [HSDB] Used as a polymer intermediate for fire-retardant varnishes and as a cotton fabric treatment to provide rot resistance; [INCHEM] Found in textile samples of cotton and wool; Used to protect textiles during transport and storage; [ExPub: Danish Ministry of the Environment]

Comments

A severe skin, eye, and respiratory tract irritant; May cause pulmonary edema; Inhalation may cause CNS effects; [ICSC] May be fatal by inhalation, ingestion, and skin absorption; [CAMEO] Corrosive to skin and eyes based on animal studies; [CHEMINFO] A strong irritant that may cause burns to skin and eyes; Inhalation hamy cause liver and kidney injury; [CHRIS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion, inhalation, and skin absorption; [Sigma-Aldrich MSDS] See "CHLOROPHENOLS."

Exposure Assessment
Vapor Pressure

2.53 mm Hg

Odor Threshold Low

0.0036 ppm

Lethal Concentration

LC50 (rat) = 390 ppm/4hr

Explanatory Notes

Flash point = 64 deg C; [ICSC] Odor threshold (threshold concentration) from CHEMINFO; The Guide in the Emergency Response Guidebook is for "Chlorophenols, liquid"

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: