Agent Name

Oxybenzone

CAS Number

131-57-7

Formula

C14-H12-O3

Major Category

Other Uses

Synonyms

(2-Hydroxy-4-methoxyphenyl)phenylmethanone; 2-Hydroxy-4-methoxybenzophenone; 4-Methoxy-2-hydroxybenzophenone; Advastab 45; Anuvex; Benzophenone, 2-hydroxy-4-methoxy-; Benzophenone-3; Chimassorb 90; Cyasorb UV 9; Cyasorb UV 9 Light Absorber; Escalol 567; HMBP; MOB; MOD; Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-; Ongrostab HMB; Oxibenzona [INN-Spanish]; Oxibenzonum; Oxybenzon; Oxybenzonum [INN-Latin]; Spectra-sorb UV 9; Sunscreen UV-15; Syntase 62; UF 3; UV 9; Uvinul 9; Uvinul M40; Uvistat 24; [ChemIDplus]

Category

Sunscreens

Description

Colorless solid; [Hawley] Pale yellow powder; [MSDSonline]

Sources/Uses

Used as an ultraviolet light absorber and stabilizer (especially in plastics), photostabilizer for synthetic resins, and topical sunscreen agent; [HSDB]

Comments

Of 7 sunscreen allergens photo-patch tested in 1990 in 355 Swedish patients, it caused the most positive reactions (15 photocontact and 1 contact); [HSDB] May cause contact dermatitis, urticaria, and irritation; [CAMEO] It is tested in a 3% concentration in petrolatum; It causes both contact and photo-contact allergic reactions; Patients may also be allergic to other benzophenone sunscreens; [Marks, p. 221] An irritant; Effects in high-dose animal studies include effects on liver, kidneys, and reproductive system; Oral LD50 (rat) = 7500 mg/kg; [MSDSonline]

Exposure Assessment
Vapor Pressure

1.42E-6 mm Hg

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Contact Dermatitis, Photoallergic

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: