Agent Name

2-Hydroxymethyl-2-nitro-1,3-propanediol

Alternative Name

Tris(hydroxymethyl)nitromethane

CAS Number

126-11-4

Formula

C4-H9-N-O5

Major Category

Other Uses

Synonyms

Tris(hydroxymethyl)nitromethane; 1,1,1-Tris(hydroxymethyl)nitromethane; 2-(Hydroxymethyl)-2-nitropropanediol; 2-Hydroxymethyl-2-nitropropane-1,3-diol; 2-Nitro-2-(hydroxymethyl)-1,3-propanediol; Cimcool wafers; Isobutylglycerol, nitro-; Methane, trimethylolnitro-; Nitroisobutylglycerol; Nitrotris(hydroxymethyl)methane; Trihydroxymethylnitromethane; Trimethylolnitromethane; Tris nitro; [ChemIDplus]

Category

Biocides/Disinfectants

Description

White solid; [Hawley] Light yellow crystals; [MSDSonline]

Sources/Uses

Used as a general disinfectant, bactericide (circulating industrial water systems, cutting oils, secondary oil field recovery waters, and paper mills), and preservative (latex paints, polishes, non-protein glues, sizings, and detergents); Also used as a disinfectant in livestock and poultry farms; [HSDB]

Comments

Two cases of allergic contact dermatitis in machinists were reported. Oral LD50 (rat) = 1900 mg/kg; No adverse effects were reported in a 90-day subchronic dermal toxicity study of rats; [HSDB] A skin and mucous membrane irritant; [Merck Index] Decomposes to formaldehyde in warm, alkaline conditions; [EPA REDs] A skin and eye irritant; [Hawley] An irritant; [MSDSonline] See "Formaldehyde."

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

1.54E-6 mm Hg

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: