Agent Name

Mercaptoethanol

CAS Number

60-24-2

Formula

C2-H6-O-S

Major Category

Other Classes

Synonyms

1-Ethanol-2-thiol; 1-Hydroxy-2-mercaptoethane; 1-Mercapto-2-hydroxyethane; 2-Hydroxy-1-ethanethiol; 2-Hydroxyethanethiol; 2-Hydroxyethyl mercaptan; 2-ME; 2-Mercapto-1-ethanol; 2-Mercaptoethanol; 2-Mercaptoethyl alcohol; 2-Thioethanol; Emery 5791; Ethanol, 2-mercapto-; Ethylene glycol, monothio-; Hydroxyethyl mercaptan; Mercaptoetanol; Monothioethylene glycol; Monothioethyleneglycol; Monothioglycol; Thioethylene glycol; Thioglycol; Thiomonoglycol; beta-Hydroxyethanethiol; beta-Hydroxyethylmercaptan; [ChemIDplus] UN2966

Category

Sulfur Compounds (Alcohols)

Description

Water-white liquid with a disagreeable odor; [Hawley] Colorless liquid with a stench; [MSDSonline]

Sources/Uses

Used to make dyestuffs, pharmaceuticals, rubber chemicals, flotation agents, insecticides, and plasticizers; Also used as solvent (dyestuffs), reducing agent, PVC stabilizer, and textile auxiliary; [Hawley]

Comments

A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] Toxic by inhalation, ingestion, and skin absorption; [CAMEO] A corrosive substance that can cause injury to the skin and eyes; May cause skin sensitization; [CHEMINFO] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause pulmonary edema; May be fatal by skin absorption; [MSDSonline] No injuries were reported to persons exposed after an accidental spill; Causes corneal scarring, severe skin irritation, and foci of hepatic necrosis in animal experiments; [AIHA]

Exposure Assessment
WEEL

0.2 ppm

Vapor Pressure

1 mm Hg

Odor Threshold Low

0.12 ppm

Odor Threshold High

0.64 ppm

Lethal Concentration

LCLo (rat) = 250 ppm/8h

Explanatory Notes

Flash point = 74 deg C; [Hawley] Odor threshold from CHEMINFO;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Skin Sensitizer

Yes

Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: