Agent Name

2-Methyl-1-butanol

CAS Number

137-32-6

Formula

C5-H12-O

Major Category

Solvents

Synonyms

1-Butanol, 2-methyl-; 2-Methyl butanol-1; 2-Methyl-n-butanol; 2-Methylbutanol; 2-Methylbutyl alcohol; Active amyl alcohol; Active primary amyl alcohol; Primary active amyl alcohol; dl-sec-Butyl carbinol; sec-Butylcarbinol; [ChemIDplus] UN1105

Category

Alcohols (<C12)

Description

Colorless liquid; [Hawley]

Sources/Uses

Used as a solvent; for organic synthesis (introduction of active amyl group); in lubricants, plasticizers, and additives for oils and paints; as a frothing agent in ore flotation; as a chemical intermediate; [HSDB] Used to manufacture liquid crystals, plant protection agents, and fragrances; to catalyze polymerization of caprolactam; and to extract crude oil; [CHEMINFO]

Comments

A skin, eye, and respiratory tract irritant; May cause CNS effects; "Swallowing the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis. The liquid defats the skin." [ICSC] Safe when used as a flavoring agent; [JECFA] In oral lethal dose studies, animals have ataxia and prostration; [OECD SIDS] An irritant; Effects in high-dose animal studies include spastic paralysis with/without sensory change; [MSDSonline]

Exposure Assessment
MAK

20 ppm

Vapor Pressure

3.12 mm Hg

Odor Threshold Low

0.12 ppm

Odor Threshold High

0.23 ppm

Explanatory Notes

Flash point = 50 deg C; [Merck Index] Odor threshold from CHEMINFO; The Guide in the Emergency Response Guidebook is for "Amyl alcohols."

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: