Agent Name

2-Nitroaniline

CAS Number

88-74-4

Formula

C6-H6-N2-O2

Major Category

Nitrogen Compounds

Synonyms

1-Amino-2-nitrobenzene; 2-Aminonitrobenzene; 2-Nitrobenzenamine; Aniline, o-nitro-; Azoene Fast Orange GR Base; Azoene Fast Orange GR Salt; Azofix Orange GR Salt; Azogene Fast Orange GR; Azoic Diazo Component 6; Benzenamine, 2-nitro-; Brentamine Fast Orange GR Base; Brentamine Fast Orange GR Salt; C.I. 37025; C.I. Azoic Diazo Component 6; CI 37025; CI Azoic Diazo Component 6; Devol Orange B; Devol Orange Salt B; Diazo Fast Orange GR; Fast Orange Base GR; Fast Orange Base JR; Fast Orange GR Base; Fast Orange GR Salt; Fast Orange O Base; Fast Orange O Salt; Fast Orange Salt GR; Fast Orange Salt JR; Hiltonil Fast Orange GR Base; Hiltosal Fast Orange GR Salt; Hindasol Orange GR Salt; Natasol Fast Orange GR Salt; ONA; Orange Base Ciba II; Orange Base IRGA II; Orange GRS Salt; Orange Salt Ciba II; Orange Salt IRGA II; Orthonitroaniline; o-Aminonitrobenzene; o-Nitraniline; o-Nitroaniline; [ChemIDplus] UN1661

Category

Nitroanilines

Description

Orange-yellow solid; [Merck Index] Darkens on exposure to light; [CHEMINFO] Orange crystalline solid; Soluble in water; [MSDSonline]

Sources/Uses

Used to make azo dyes and pigments, vat dyes, photographic antifogging agents, coccidiostats, and ortho-phenylenediamine; [HSDB] Used to make benzotriazoles, cutting fluids, and pharmaceuticals; [SIDSUNEP]

Comments

Highly toxic; May be absorbed through skin; May induce methemoglobinemia and cyanosis; Prolonged exposure may cause damage to the liver; [Merck Index] Can induce methemoglobinemia; [ICSC] A skin, eye, nose, and throat irritant; [HSDB] An irritant; [MSDSonline]

Reference Link

OECD SIDS: 2-Nitroaniline - 2001

Exposure Assessment
Vapor Pressure

0.00277 mm Hg

Lethal Concentration

LC50 (rat) > 2,529 mg/m3/4h

Explanatory Notes

Flash point = 168 deg C; [Hawley]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.