Agent Name

2-Octanone

Alternative Name

Hexyl methyl ketone

CAS Number

111-13-7

Formula

C8-H16-O

Major Category

Solvents

Synonyms

Hexyl methyl ketone; 2-Octanone (natural); 2-Oxooctane; Methyl hexyl ketone; Methyl n-hexyl ketone; n-Hexyl methyl ketone; [ChemIDplus] Octan-2-one; [JECFA] UN1224

Category

Ketones (<C12)

Description

Colorless liquid with a pleasant odor; [Hawley]

Sources/Uses

Used in perfumes, flavorings, and odorants; Also used as a high-boiling solvent (especially for epoxy resin coatings); Also used in leather finishes and nitrocellulose lacquers; [Hawley] Used as a flavoring agent; [FDA]

Comments

May cause mild irritation; Inhalation of high concentrations can cause CNS depression; [HSDB] Safe when used as a flavoring agent in food; [JECFA] An irritant; Harmful by skin absorption; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

1.35 mm Hg

Odor Threshold Low

248 ppm

Lethal Concentration

LC50 (rat) > 2,132 ppm/6hr

Explanatory Notes

Odor threshold from HSDB; The Guide in the Emergency Response Guidebook is for "Ketones, liquid, n.o.s."

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: