Agent Name

Phenylethyl alcohol

Alternative Name

2-Phenylethanol

CAS Number

60-12-8

Formula

C8-H10-O

Major Category

Other Classes

Synonyms

2-Phenylethanol; 1-Phenyl-2-ethanol; 2-Hydroxyethylbenzene; 2-PEA; 2-Phenethyl alcohol; 2-Phenylethyl alcohol; Benzeneethanol; Benzyl carbinol; Benzylcarbinol; Benzylmethanol; Ethanol, 2-phenyl-; Methanol, benzyl-; PEA; Phenethanol; Phenethyl alcohol; Phenethyl alcohol (natural); beta-Fenethylalkohol [Czech]; beta-Fenylethanol [Czech]; beta-Hydroxyethylbenzene; beta-Phenylethanol; [ChemIDplus]

Category

Alcohols and Polyols, Other

Description

Colorless liquid with a floral odor; [Hawley]

Sources/Uses

Found in many natural essential oils; [Merck Index] Used as a flavoring agent in foods and beverages; as a fragrance in perfumes, cosmetics, detergents, synthetic rose oils, and soaps; and as an antibacterial and preservative; [HSDB] Present in food at <20 ppm and in perfumes at 2%; [REPROTOX]

Comments

Higher alcohols are not highly toxic in the industrial setting; Can cause liver injury, somnolence, and respiratory depression in experimental animals; [HSDB] General anesthetic effect after subcutaneous injection of mice; [RTECS] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; Possible toxic effects on human reproduction; [ICSC] May cause corneal injury; [CHEMINFO] Safe when used as a flavoring agent in food; [JECFA] Has teratogenic effects in rats at doses >4.3 mg/kg; [REPROTOX]

Exposure Assessment
Vapor Pressure

0.08 mm Hg

Odor Threshold Low

7.02 ppm

Lethal Concentration

LC50 (rat) > 500 mg/m3

Explanatory Notes

Flash point = 102 deg C; [Hawley] Odor threshold (detection) from CHEMINFO;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: