Agent Name

2-Vinylpyridine

CAS Number

100-69-6

Formula

C7-H7-N

Major Category

Nitrogen Compounds

Synonyms

2-Ethenylpyridine; 2VP; Pyridine, 2-ethenyl-; Pyridine, 2-vinyl-; alpha-Vinylpyridine; [ChemIDplus] UN3073

Category

Pyridines

Description

Colorless liquid with an unpleasant odor; [HSDB]

Sources/Uses

Used as an acrylic fiber comonomer, grafting reagent (ashless lubricant dispersants), and chemical intermediate; [HSDB]

Comments

A skin, eye, nose, and mucous membrane irritant; May cause skin burns and sensitization; Emergency treatment: "Pyridine"; Pyridine is an irritant that causes CNS depression after ingestion of 1/2 cup or inhalation of 6-12 ppm; It can cause liver and kidney injury; [HSDB] May cause delayed burns to skin; A severe eye and respiratory tract irritant; May cause skin sensitization; [ICSC] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; May be absorbed through skin; [Alfa Aesar MSDS] May cause burns; Toxic if swallowed; Harmful if inhaled; May cause allergic skin reactions; [Aldrich MSDS] Vinylpyridines, stabilized (UN3073) has warning of explosive polymerization; [ERG 2016] See "Pyridine."

Reference Link

Cutaneous and systemic sequelae from exposure to 2... [Contact Dermatitis. 2006] - PubMed result

Exposure Assessment
Odor Threshold Low

0.3 ppm

Odor Threshold High

0.5 ppm

Lethal Concentration

LC50 (rat) = 610 mg/m3

Explosive Polymerization

Yes

Explanatory Notes

VP = 10 mm Hg at 44.5 deg C; [HSDB] Odor threshold form HSDB; The Guide in the Flash point = 42 deg C; [ICSC] Emergency Response Guidebook is for "Vinylpyridines, stabilized."

Adverse Effects
Skin Sensitizer

Yes

Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: