Agent Name

3,4-Diaminotoluene

CAS Number

496-72-0

Formula

C7-H10-N2

Major Category

Nitrogen Compounds

Synonyms

1,2-Benzenediamine, 4-methyl-; 1,2-Diamino-4-methylbenzene; 3,4-Diamino-1-methylbenzene; 3,4-Toluenediamine; 3,4-Toluylenediamine; 3,4-Tolylenediamine; 4-Methyl-1,2-benzenediamine; 4-Methyl-1,2-diaminobenzene; 4-Methyl-1,2-phenylenediamine; 4-Methyl-o-phenylenediamine; Toluene-3,4-diamine; Toluenediamine; [ChemIDplus] UN2811

Category

Amines, Aromatic

Description

Solid; [HSDB] Colorless to brownish-purple solid; [CAMEO]

Sources/Uses

Used as a chemical intermediate, research chemical, and component in hair dyes; [HSDB] Only commercially available as 40:60 mixture of the ortho (2,3- and 3,4) isomers used as co-reactants or raw materials in the production of dyes, corrosion inhibitors, urethane products, and rubber antioxidants; Also used to lesser extent to make mercaptotoluimidazole and its zinc salt (specialty antioxidants in nitrile rubber elastomers) and as substitute for o-phenylenediamine in epoxy resin curing; The commercial mixture may be represented by CAS #'s 25376-45-8 and 26966-75-6 (although these CAS #s may also be used for other isomeric mixtures); [OECD SIDS]

Comments

External application to rabbit eyes scored 7 on a scale of 1-10 (10 being most severe) for degree of injury (2,3/3,4 mixture); Emergency treatment: Methemoglobinemia; [HSDB] A skin and eye irritant; [CAMEO] An irritant; Harmful by ingestion, inhalation, or skin absorption; [Aldrich MSDS] See "2,4-Diaminotoluene."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

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