Agent Name

3,4-Dimethylphenol

Alternative Name

3,4-Xylenol

CAS Number

95-65-8

Formula

C8-H10-O

Major Category

Other Classes

Synonyms

1,3,4-Xylenol; 1-Hydroxy-3,4-dimethylbenzene; 3,4-DMP; 4,5-Dimethylphenol; 4-Hydroxy-1,2-dimethylbenzene; Phenol, 3,4-dimethyl-; [ChemIDplus] UN2261

Category

Phenols

Description

Colorless to tan solid; Hygroscopic; [CAMEO] White or yellow crystalline solid; [MSDSonline]

Sources/Uses

Used as a starting material for phenolic resins; [HSDB]

Comments

Safe when used as a flavoring agent in food; [JECFA] Causes tetany, hepatitis, and renal tubular changes in lethal-dose feeding studies of rats; [RTECS] Toxic by ingestion; [HSDB] Corrosive to tissues; May cause spasm, inflammation, and edema of the larynx and bronchi after inhalation; Can cause liver and kidney damage; [CAMEO] May cause burns; [eChemPortal: ESIS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; May be absorbed through skin; Effects in high-dose animal studies include acute tubular necrosis and hepatitis; [MSDSonline] See "Phenol."

Exposure Assessment
Vapor Pressure

0.03 mm Hg

Explanatory Notes

Odor threshold = 0.003 mg/m3 (detection in air); [HSDB] The Guide in the Emergency Response Guidebook is for "Xylenols, solid."

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.