Agent Name

3,4-Dimethylphenol

Alternative Name

3,4-Xylenol

CAS Number

95-65-8

Formula

C8-H10-O

Major Category

Other Classes

Synonyms

1,3,4-Xylenol; 1-Hydroxy-3,4-dimethylbenzene; 3,4-DMP; 4,5-Dimethylphenol; 4-Hydroxy-1,2-dimethylbenzene; Phenol, 3,4-dimethyl-; [ChemIDplus] UN2261

Category

Phenols

Description

Colorless to tan solid; Hygroscopic; [CAMEO] White or yellow crystalline solid; [MSDSonline]

Sources/Uses

Used as a starting material for phenolic resins; [HSDB]

Comments

Safe when used as a flavoring agent in food; [JECFA] Causes tetany, hepatitis, and renal tubular changes in lethal-dose feeding studies of rats; [RTECS] Toxic by ingestion; [HSDB] Corrosive to tissues; May cause spasm, inflammation, and edema of the larynx and bronchi after inhalation; Can cause liver and kidney damage; [CAMEO] May cause burns; [eChemPortal: ESIS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; May be absorbed through skin; Effects in high-dose animal studies include acute tubular necrosis and hepatitis; [MSDSonline] See "Phenol."

Exposure Assessment
Vapor Pressure

0.03 mm Hg

Explanatory Notes

Odor threshold = 0.003 mg/m3 (detection in air); [HSDB] The Guide in the Emergency Response Guidebook is for "Xylenols, solid." See "2018 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.