Agent Name

tert-Butyl acetate

CAS Number

540-88-5

Formula

C6-H12-O2

Major Category

Solvents

Synonyms

1,1-Dimethyl acetate; Acetic acid, 1,1-dimethylethyl ester; Acetic acid, tert-butyl ester; TLA; Texaco lead appreciator; t-Butyl acetate; tert-Butyl acetate; tert-Butyl ethanoate; [ChemIDplus] UN1123

Category

Esters (<C12)

Description

Colorless liquid with a fruity odor; [NIOSH]

Sources/Uses

Used as a solvent (industrial coatings, inks, adhesives, cleaners) and gasoline additive; Bananas and other fruits are food sources. [ACGIH]

Comments

Liver changes were seen in animals exposed to 7900 mg/m3. [ACGIH] A throat and eye irritant; [CAMEO] Inhalation of high concentrations can cause CNS depression; [CHEMINFO]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

50 ppm

STEL (ACGIH)

150 ppm

PEL (OSHA)

200 ppm

MAK

50 ppm

IDLH (NIOSH)

1500 ppm

Excerpts from Documentation for IDLHs

Exposures of 200 to 300 ppm cause slight irritation of the eyes and nose, and short exposures to 3,300 ppm cause extreme irritation of the eyes and nose [ILO 1983].

Vapor Pressure

47 mm Hg

Odor Threshold Low

4 ppm

Odor Threshold High

47 ppm

Explanatory Notes

IDLH = 10% LEL (lower explosive limit); Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; Flash point = 72 deg F;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: