Agent Name

3-Methylindole

Alternative Name

Skatole

CAS Number

83-34-1

Formula

C9-H9-N

Major Category

Nitrogen Compounds

Synonyms

1H-Indole, 3-methyl-; 3-MI; 3-Methyl-1H-indole; 3-Methyl-4,5-benzopyrrole; Indole, 3-methyl-; Scatole; Skatol; beta-Methylindole; [ChemIDplus]

Category

Indoles

Description

White to brownish solid with a fecal odor; [Merck Index] Odor becomes pleasant and sweet at very low concentrations; [HSDB] White crystalline flakes with a stench; [MSDSonline]

Sources/Uses

Used in perfume fixatives, artificial civet (musk), food flavoring, and experimental veterinary medications; [HSDB]

Comments

Caused no irritation in humans following 24 hour closed patch test (2% in petrolatum); [HSDB] Lethal doses by intravenous and oral routes produced pulmonary lesions in cattle; [RTECS] Safe when used as a flavoring agent in food; [JECFA] See "Indole."

Exposure Assessment
Vapor Pressure

0.0055 mm Hg

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