Agent Name

3-Picoline

CAS Number

108-99-6

Formula

C6-H7-N

Major Category

Nitrogen Compounds

Synonyms

3-Methylpyridine; Pyridine, 3-methyl-; beta-Methylpyridine; beta-Picoline; m-Methylpyridine; m-Picoline; [ChemIDplus] UN2313

Category

Pyridines

Description

Colorless liquid with a sweet, but not unpleasant odor; [Merck Index]

Sources/Uses

Used as a solvent (pharmaceuticals, resins, and dyestuffs), rubber accelerator, laboratory reagent, and chemical intermediate; [HSDB] Picolines are constituents in cigarette smoke, bone oil, coal tar, and coke oven emissions. [AIHA]

Comments

A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation of high concentrations can cause unconsciousness; The liquid defats the skin; [ICSC] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; May be absorbed through skin; Causes CNS depression in high-dose animal studies; [MSDSonline] An irritant that can cause CNS depression; In one case, a worker exposed for 11 years had elevated liver enzymes; Liver changes occur in rats exposed to chronic high doses; [AIHA]

Exposure Assessment
WEEL

2 ppm, STEL = 5 ppm

Vapor Pressure

6.05 mm Hg

Lethal Concentration

LCLo (rat) = 11,820 mg/m3/5h

Explanatory Notes

Flash point = 38 deg C; [ICSC] The Guide in the Emergency Response Guidebook is for "Picolines."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

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