Agent Name

3-t-Butyl-4-hydroxyanisole

CAS Number

121-00-6

Formula

C11-H16-O2

Major Category

Other Uses

Synonyms

2(3)-tert-Butyl-4-hydroxyanisole; 2-(1,1-Dimethylethyl)-4-methoxy-phenol; 2-tert-Butyl-4-methoxyphenol; 3-BHA; 3-Tert-butyl-4-hydroxyanisole; 3-tert-Butyl-4-hydroxyanisole; 4-Methoxy-2-tert-butylphenol; Butylated hydroxyanisole I (D); Phenol, 2-(1,1-dimethylethyl)-4-methoxy-; Phenol, 2-tert-butyl-4-methoxy-; [ChemIDplus]

Category

Preservatives

Description

Faintly beige fine plates; [MSDSonline]

Sources/Uses

Used as a food additive (oxidation inhibitor); [HSDB] Used as preservative in foods, cosmetics, topical medications, animal feeds, rubber, plastics, pints, and glues; [Marks, p. 139]

Comments

Permitted in food at levels up to 200 ppm; Despite widespread use, allergic contact dermatitis is rare. Percent positive patch test responses were 0.2% in a US series in 1992-4; Contact urticaria has been reported; [Marks, p. 138-9] Commercial BHA is usually an 85:15 mixture of 3-t-butyl- and 2-t-butyl-isomers; [HSDB] May cause skin sensitization; [eChemPortal: ERMA] May cause irritation; [MSDSonline]

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Health Studies

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Chemical Information

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