Agent Name

4,4'-Diacetylbenzidine

CAS Number

613-35-4

Formula

C16-H16-N2-O2

Major Category

Nitrogen Compounds

Synonyms

4',4'''-Biacetanilide; 4,4'-Diacetamidobiphenyl; 4,4'-Diacetylaminobiphenyl; Acetamide, N,N'-(1,1'-biphenyl)-4,4'-diylbis-; Acetamide, N,N'-4,4'-biphenylylenebis-; Benzidine, N,N'-diacetyl-; Biphenyl, 4,4'-diacetamido-; Diacetylbenzidine; N,N'-(1,1'-Biphenyl)-4,4'-diylbis-acetamide; N,N'-4,4'-Biphenylylenebisacetamide; N,N'-Diacetyl benzidine; N,N'-Diacetylbenzidine; [ChemIDplus]

Category

Benzidine and Derivatives

Description

White solid; [HSDB] Pale yellow powder; [TCI MSDS]

Sources/Uses

Used as a research chemical and to prepare 3,3'-Dichlorobenzidine and 3,3'-Dinitrobenzidine; [HSDB]

Comments

May irritate eyes and respiratory tract; May cause methemoglobinemia, anemia, and kidney injury; [ICSC] Glomerular lesions in feeding study of rats developed within a few months; IP injection in rats causes hepatocellular degeneration and changes in bile canaliculi; Evidence of carcinogenicity and mutagenicity in experimental animals; Emergency treatment: Methemoglobinemia; [HSDB] See "Benzidine."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.