Agent Name

sec-Butyl alcohol

Alternative Name

sec-Butanol

CAS Number

78-92-2

Formula

C4-H10-O

Major Category

Solvents

Synonyms

sec-Butanol; 1-Methyl propanol; 1-Methyl-1-propanol; 1-Methylpropyl alcohol; 2-Butanol (natural); 2-Butyl alcohol; 2-Hydroxybutane; Alcool butylique secondaire [French]; Butan-2-ol; Butanol secondaire [French]; Butyl alcohol, sec-; Butylene hydrate; CCS 301; Ethyl methyl carbinol; Ethylmethyl carbinol; Methyl ethyl carbinol; Methylethyl carbinol; Methylethylcarbinol; s-Butanol; s-Butyl alcohol; sec-Butanol; [ChemIDplus] UN1993

Category

Alcohols (<C12)

Description

Colorless liquid with a strong, pleasant odor; [NIOSH]

Sources/Uses

Used as a solvent, paint remover, and cleaner; also used to manufacture other organic compounds; [ACGIH]

Comments

A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Reference Link

NIOSH Occupational Health Guidelines for Chemical Hazards: sec-Butyl alcohol

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

100 ppm

PEL (OSHA)

150 ppm

IDLH (NIOSH)

2000 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by Patty [1963] that 10,670 ppm for 225 minutes and 16,000 ppm for 160 minutes were fatal for mice [Weese 1928]. According to Patty [1963], at 20,000 ppm it took 12 to 20 minutes to produce prostration in mice and 40 minutes to produce narcosis; no deaths occurred [Starrek 1938]. The chosen IDLH is probably conservative.

Vapor Pressure

18.3 mm Hg

Odor Threshold Low

0.12 ppm

Odor Threshold High

13.8 ppm

Lethal Concentration

LCLo (rat) = 16,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 3.2 ppm); Flash point = 75 deg F;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: