Agent Name

sec-Butyl alcohol

Alternative Name

sec-Butanol

CAS Number

78-92-2

Formula

C4-H10-O

Major Category

Solvents

Synonyms

sec-Butanol; 1-Methyl propanol; 1-Methyl-1-propanol; 1-Methylpropyl alcohol; 2-Butanol (natural); 2-Butyl alcohol; 2-Hydroxybutane; Alcool butylique secondaire [French]; Butan-2-ol; Butanol secondaire [French]; Butyl alcohol, sec-; Butylene hydrate; CCS 301; Ethyl methyl carbinol; Ethylmethyl carbinol; Methyl ethyl carbinol; Methylethyl carbinol; Methylethylcarbinol; s-Butanol; s-Butyl alcohol; sec-Butanol; [ChemIDplus] UN1993

Category

Alcohols (<C12)

Description

Colorless liquid with a strong, pleasant odor; [NIOSH]

Sources/Uses

Used as a solvent, paint remover, and cleaner; also used to manufacture other organic compounds; [ACGIH]

Comments

A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

100 ppm

PEL (OSHA)

150 ppm

IDLH (NIOSH)

2000 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by Patty [1963] that 10,670 ppm for 225 minutes and 16,000 ppm for 160 minutes were fatal for mice [Weese 1928]. According to Patty [1963], at 20,000 ppm it took 12 to 20 minutes to produce prostration in mice and 40 minutes to produce narcosis; no deaths occurred [Starrek 1938]. The chosen IDLH is probably conservative.

Vapor Pressure

18.3 mm Hg

Odor Threshold Low

0.12 ppm

Odor Threshold High

13.8 ppm

Lethal Concentration

LCLo (rat) = 16,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 3.2 ppm); Flash point = 75 deg F;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: