Agent Name

4,4'-Dithiodimorpholine

CAS Number

103-34-4

Formula

C8-H16-N2-O2-S2

Major Category

Nitrogen Compounds

Synonyms

4,4'-Dithiobis(morpholine); 4,4'-Dithiomorpholine; Accel R; Bismorpholino disulfide; Deovulc M; Dimorpholine N,N'-disulfide; Dimorpholine disulfide; Dimorpholino disulfide; Disulfide, dimorpholino-; Dithiobismorpholine; Morpholine disulfide; Morpholine, 4,4'-dithiobis-; Morpholine, 4,4'-dithiodi-; Morpholine, N,N'-disulfide-; Morpholino disulfide; Morpholinodisulfide; N,N'-Bismorpholine disulfide; N,N'-Dithiodimorfolin [Czech]; N,N-Dithiodimorpholine; Sanfel R; Sulfasan; Sulfasan R; Vanax A; Vulnoc; [ChemIDplus] DTDM; [EPA]

Category

Morpholines

Description

Gray to tan solid; [Hawley] White solid; [MSDSonline]

Sources/Uses

Used as a stain protector for rubber, a vulcanizer (sulfur donor) and accelerator for natural and synthetic rubbers, a fungicide, and a curing agent for poly(fluoroalkoxyphosphazenes); [HSDB]

Comments

Effects in high-dose feeding studies of rats include anemia and liver changes; Emergency treatment: "Morpholine"; Morpholine is an irritant that can cause corneal damage; Liver and kidney injury occur in lethal-dose studies of laboratory animals; [HSDB] Causes abnormal liver function tests in feeding studies of rats; [RTECS] Not irritating to skin but irritating to eyes in rabbits; Not sensitizing; Decrease in fetal viability and body weight, and minor increase in malformed fetuses at materno-toxic doses; Not mutagenic; [EPA Hazard Characterization Document] Irritating but not sensitizing in patch test with ten volunteers; [EPA HPVIS] May cause irritation; [Aldrich MSDS]

Exposure Assessment
Vapor Pressure

3.05E-5 mm Hg

Lethal Concentration

LC50 (mice) = 1,624 mg/m3/4h

Explanatory Notes

Flash point = 121 deg C; [HSDB]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: