Agent Name

4-Acetylaniline

CAS Number

99-92-3

Formula

C8-H9-N-O

Major Category

Nitrogen Compounds

Synonyms

1-(4-Aminophenyl)ethanone; 4'-Aminoacetophenone; Acetophenone, 4-amino-; Acetophenone, p-amino-; Ethanone, 1-(4-aminophenyl)-; p-Acetylaniline; p-Aminoacetofenonu [Polish]; p-Aminoacetophenone; p-Aminoacetylbenzene; [ChemIDplus]

Category

Amines, Aromatic

Description

Yellow solid with a pleasant odor; [HSDB] Tan crystalline solid; [MSDSonline]

Sources/Uses

Used as intermediate for flavaniline (basic dye), acetohexamide, and an oral hypoglycemic drug; [HSDB]

Comments

A strong inducer of methemoglobin in vivo; Emergency treatment: "Aniline"; [HSDB] Methemoglobinemia observed in oral lethal-dose study of dogs; [RTECS] An irritant; Toxic if swallowed; May be harmful by inhalation or skin absorption; [Aldrich MSDS] See "Aniline."

Exposure Assessment
Vapor Pressure

0.00989 mm Hg

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

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