Agent Name

tert-Butyl chromate

CAS Number

1189-85-1

Formula

C8-H18-Cr-O4

Major Category

Metals

Synonyms

di-tert-Butyl ester of chromic acid; Bis (tert-butyl) chromate; t-Butyl chromate; [CHEMINFO]

Category

Metals, Organic Compounds

Description

Liquid; Note: Solidifies at 23-32 degrees F; [NIOSH]

Sources/Uses

Used to synthesize catalysts and other organic chemicals; also used as a curing agent for polyurethanes and polyolefins, e.g., polypropylene and polyethylene; [NIOSH Guidelines for Chemical Hazards]

Comments

Can cause acid-like burns; chronic exposure may result in kidney and liver damage; [NIOSH Guidelines for Chemical Hazards] May cause irritation of the skin, eyes, and respiratory tract; May have CNS effects, e.g., drowsiness; [CAMEO] Potential respiratory tract sensitizer; [CHEMINFO] See Chromium.

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

Ceiling (ACGIH)

0.1 mg/m3, as CrO3

PEL (OSHA)

0.005 mg/m3, as CrO3

IDLH (NIOSH)

15 mg/m3, as Cr(VI)

Excerpts from Documentation for IDLHs

Very little toxicological data are available concerning the effects produced by exposure to tertbutyl chromate. Because AIHA [1965] reported that the severity of the health hazard is low for acute exposure to chromic acid, by analogy it is assumed that the hazard is also low for acute exposure to tertbutyl chromate. Therefore, the chosen IDLH is based on an analogy with chromic acid and chromates, which has an IDLH of 30 mg/m3 (as CrO3).

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: