Agent Name

4-Chloro-2-methylphenol

CAS Number

1570-64-5

Formula

C7-H7-Cl-O

Major Category

Other Classes

Synonyms

2-Methyl-4-chlorophenol; 4-Chloro-2-cresol; 4-Chloro-o-cresol; Phenol, 4-chloro-2-methyl-; o-Cresol, 4-chloro-; p-Chloro-o-cresol; [ChemIDplus] 5-Chloro-2-hydroxytoluene; PCOC; [CAMEO] 4-Chlor-ortho-kresol; 4-Chloro, 2-methyl phenol; 4-CHLORO-ORTHO-CRESOL; P.C.O.C.; Para chloro 2-cresol; Para chloro 2-methyl phenol; Para chloro ortho cresol; Para Chloro ortho cresol; Para orthochlorocresol; PARA-CHLORO-ORTHO-CRESOL; [IUCLID] UN2669; UN3437

Category

Chlorophenols

Description

Pale yellow solid; [HSDB] Dark red solid; [CAMEO] White to brown solid; [CHEMINFO] White or brown crystalline solid; [MSDSonline]

Sources/Uses

Used to make herbicides (Mecoprop, MCPA, and MCPB), as an additive tracer for resist plasma etching, and as a disinfectant; [HSDB] "Metabolite of 2-methyl-4-chlorophenoxyacetic acid & other phenoxyacetic acid herbicides." [ChemIDplus] Used as a closed system intermediate in phenoxy herbicide production; [IUCLID]

Comments

A skin, eye, and mucous membrane irritant; [CAMEO] A corrosive substance that can cause injury to the skin and eyes, based on animal studies; [CHEMINFO] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Can cause pulmonary edema; [ICSC] Chlorocresol causes contact urticaria (both immune and non-immune); [Kanerva, p. 219] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline] See "CHLOROPHENOLS." See "p-Chloro-m-cresol."

Exposure Assessment
Vapor Pressure

0.02 mm Hg

Lethal Concentration

LC50 (rat) = 900 mg/m3/4h

Explanatory Notes

Flash point = 78 deg C; [CHEMINFO] The Guide in the Emergency Response Guidebook is for "Chlorocresols, solid."

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: