Agent Name

4-Picoline

CAS Number

108-89-4

Formula

C6-H7-N

Major Category

Nitrogen Compounds

Synonyms

4-Methylpyridine; Ba 35846; Pyridine, 4-methyl-; gamma-Methylpyridine; gamma-Picoline; p-Methylpyridine; p-Picoline; [ChemIDplus] UN2313

Category

Pyridines

Description

Colorless liquid with an obnoxious, sweetish odor; [HSDB]

Sources/Uses

Used as a chemical intermediate, solvent (pharmaceuticals, resins, dyestuffs, rubber accelerators, pesticides, and waterproofing agents), laboratory reagent, catalyst, and curing agent; [HSDB] Picolines are constituents in cigarette smoke, bone oil, coal tar, and coke oven emissions. [AIHA]

Comments

A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation of high concentrations can cause unconsciousness; The liquid defats the skin; [ICSC] An irritant; Can be absorbed through skin; [MSDSonline] An irritant that can cause CNS depression; Liver changes occur in rats exposed to chronic high doses; [AIHA] See "Pyridine."

Exposure Assessment
WEEL

2 ppm, STEL = 5 ppm

Vapor Pressure

5.77 mm Hg

Lethal Concentration

LCLo (rat) = 1,000 ppm/4h

Explanatory Notes

Flash point = 57 deg C; [ICSC] The Guide in the Emergency Response Guidebook is for "Picolines."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Other Information

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