Agent Name

8-Hydroxyquinoline

CAS Number

148-24-3

Formula

C9-H7-N-O

Major Category

Nitrogen Compounds

Synonyms

1-Azanaphthalene-8-ol; 8-Chinolinol [Czech]; 8-Hydroxy-chinolin [German]; 8-Hydroxychinolin; 8-OQ; 8-Oxyquinoline; 8-Quinol; Bioquin; Fennosan; Fennosan H 30; Fennosan HF-15; Hydroxybenzopyridine; Oxin; Oxine; Oxybenzopyridine; Oxychinolin; Oxyquinoline; Phenopyridine; Quinoline, 8-hydroxy-; Quinophenol; Tumex; o-Oxychinolin [German]; [ChemIDplus]

Category

Quinolines

Description

White solid with a phenolic odor; [Hawley] White or tan powder; [MSDSonline]

Sources/Uses

Used as an antiseptic, hydrogen peroxide stabilizer, chemical reagent, corrosion inhibitor, stabilizer in nylon, chelating agent, fungicide, and brightener of steel sheets in electroplating baths; Also used to make dyes; [HSDB]

Comments

Oral LD50 (rat) = 1.2 g/kg; Causes convulsions when given intraperitoneally(ip) with an LD50 (rat) = 50 mg/kg; [HSDB] An irritant; Harmful if swallowed; Causes mutagenic effects and tumors in animals after high-dose feeding studies; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.0016 mm Hg

Lethal Concentration

LC50 (rat) > 1,210 mg/m3/6h

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Processes

Industrial Processes with risk of exposure: