Agent Name

Acephate

CAS Number

30560-19-1

Formula

C4-H10-N-O3-P-S

Major Category

Pesticides

Synonyms

75 SP; Acephat; Acephat [German]; Acephate, technical; Acetamidophos; Acetylphosphoramidothioic acid O,S-dimethyl ester; Chevron Orthene; Chevron RE 12,420; ENT 27822; N-(Methoxy(methylthio)phosphinoyl)acetamide; O,S-Dimethyl acetylphosphoramidothioate; O,S-Dimethylacetylphosphoroamidothioate; Orthene; Orthene-755; Ortho 124120; Ortran; Ortril; RE 12420; Phosphoramidothioic acid, N-acetyl-, O,S-dimethyl ester; Phosphoramidothioic acid, acetyl-, O,S-dimethyl ester; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless to white solid; [HSDB] Colorless crystalline solid with a stench; [MSDSonline]

Sources/Uses

Used as a contact and systemic insecticide for field, fruit, and vegetable crops, forestry, food handling, ornamentals, and household applications; Also used for control of parasites in farm animals; [HSDB] Used in industrial, commercial, and other public and non-agricultural areas; [Reference #1]

Comments

May cause cholinesterase inhibition; [ICSC] At doses non-toxic maternally, embryonic development was not adversely effected in mice; High dose studies of mice caused dose-dependent rise of abnormalities in sperm; No human data available; [REPROTOX] Methamidophos (CAS# 10265-92-6) is an environmental degradate; "Laboratory data indicate that acephate and its degradate may pose chronic risk to mammals by affecting the reproductive capacity of mammals (i.e., by reducing the viability of pups and body weight); however, there are no field data to corroborate this." [Reference #1] See "Methamidophos."

Restricted

Banned in the EU for use as a biocide and agricultural insecticide; [eChemPortal: ESIS]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Vapor Pressure

1.7E-6 mm Hg

Lethal Concentration

LCLo (mice) = 2,200 mg/m3/5h

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: