Agent Name

Camphor, synthetic

CAS Number

76-22-2

Formula

C10-H16-O

Major Category

Other Classes

Synonyms

1,7,7-Trimethylbicyclo(2.2.1)-2-heptanone; 1,7,7-Trimethylnorcamphor; 2-Bornanone; 2-Camphanone; 2-Kamfanon [Czech]; 2-Keto-1,7,7-trimethylnorcamphane; Alphanon; Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-; Bicyclo(2.2.1)heptane-2-one, 1,7,7-trimethyl-; Bornane, 2-oxo-; Camphor; Camphor, synthetic; DL-Camphor; Gum camphor; Huile de camphre [French]; Kampfer [German]; Matricaria camphor; Norcamphor, 1,7,7-trimethyl-; Root bark oil; Spirit of camphor; dl-Camphor; [ChemIDplus] UN2717

Category

Other Organic Compounds

Description

Colorless or white crystals with a penetrating, aromatic odor; [NIOSH]

Sources/Uses

Used as a plasticizer and chemical intermediate; also used as an additive to explosives, varnishes, lacquers, insecticides, fungicides, pharmaceuticals, cosmetics, and flavorings; [ACGIH]

Comments

Workers exposed to greater than 2 ppm (12.6 mg/m3) report irritation of the eyes and nose and loss of the sense of smell. Camphor causes convulsions in experimental animals and in humans after ingestion of high doses. [ACGIH] Included in list of "established contact allergens in humans"; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] May cause elevated liver enzymes in poisoning cases after ingestion; [HSDB] See "L-Camphor."

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

12 mg/m3

STEL (ACGIH)

19 mg/m3

PEL (OSHA)

2 mg/m3

IDLH (NIOSH)

200 mg/m3

Excerpts from Documentation for IDLHs

It has been reported that concentrations during camphor processing and packaging ranged from 33 to 194 mg/m3; workers had no complaints other than slight eye irritation and afternoon drowsiness [Gronka et al. 1969].

Vapor Pressure

0.65 mm Hg

Odor Threshold Low

0.0026 mg/m3

Odor Threshold High

0.96 mg/m3

Lethal Concentration

LCLo (mice) = 400 mg/m3/3H

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.079 ppm); Flash point = 66 deg C;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: