Agent Name

Acesulfame

CAS Number

33665-90-6

Formula

C4-H5-N-O4-S

Major Category

Nitrogen Compounds

Synonyms

1,2,3-Oxathiazin-4(3H)-one, 6-methyl-, 2,2-dioxide; 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one-2,2-dioxide; 6-Methyl-1,2,3-oxathiazin-4(3H)-on 2,2-dioxid; 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide; 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide; Acesulfamo; Acesulfamo [INN-Spanish]; Acesulfamum; Acesulfamum [INN-Latin]; Acetosulfam; [ChemIDplus]

Category

Other Nitrogen Compounds

Description

Solid; [Merck Index]

Sources/Uses

Used as a non-nutritive artificial sweetener and in carriers for edible compounds; [HSDB]

Comments

Potassium salt: Oral LD50 (rat) = 7,430 mg/kg; Not irritating to rabbit skin but irritating to rabbit eyes; 90-day feeding study of rats produced minor effects at highest tested dose of 10%, but no serum enzyme, gross pathological, or histological changes; No adverse effects observed in two year feeding study of dogs (doses up to 3% corresponding to 900 mg/kg/day); No evidence of reproductive, developmental, or teratogenic toxicity in rats; Emergency treatment: "Non-toxic ingestion"; [HSDB]

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