Agent Name

Caprolactam

CAS Number

105-60-2

Formula

C6-H11-N-O

Major Category

Plastics & Rubber

Synonyms

1,6-Hexalactam; 1,6-Hexolactam; 1-Aza-2-cycloheptanone; 2-Azacycloheptanone; 2-Ketohexamethylenimine; 2-Oxohexamethyleneimine; 2-Oxohexamethylenimine; 2-Perhydroazepinone; 2H-Azepin-2-one, hexahydro-; 2H-Azepin-7-one, hexahydro-; 6-Aminocaproic acid lactam; 6-Aminohexanoic acid cyclic lactam; 6-Caprolactam; 6-Hexanelactam; A1030; Aminocaproic lactam; Caprolactam; Caprolactam monomer; Caprolattame [French]; Capron PK4; Cyclohexanone iso-oxime; Epsylon kaprolaktam [Polish]; Extrom 6N; Hexahydro-2-azepinone; Hexahydro-2H-azepin-2-one; Hexamethylenimine, 2-oxo-; Hexanoic acid, 6-amino-, cyclic lactam; Hexanoic acid, 6-amino-, lactam; Hexanolactam; Hexanone isoxime; Hexanonisoxim [German]; Kapromine; Stilon; e-Kaprolaktam [Czech]; epsilon-Caprolactam; [ChemIDplus] UN8027

Category

Other Monomers

Description

White, crystalline solid or flakes with an unpleasant odor; Note: Significant vapor concentrations would be expected only at elevated temperatures; [NIOSH]

Sources/Uses

Used as "a monomer for synthetic fibers, plastics, coatings, plasticizers, and paint vehicles and as a cross-linking agent for polyurethanes." [ACGIH]

Comments

May cause skin sensitization; A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] Liver and kidney changes occur in subchronic animal studies using intraperitoneal doses. [ACGIH]

Reference Link

NIOSH Occupational Health Guidelines for Chemical Hazards: Caprolactam

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 mg/m3, inhalable fraction and vapor

MAK

5 mg/m3, inhalable fraction

Vapor Pressure

0.0019 mm Hg

Lethal Concentration

LC50 (rat) = 300 mg/m3/2h

Explanatory Notes

Flash point = 110 deg C;

Reference Link

ICSC: Caprolactam

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Not Suspected

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: