Agent Name

Captan

CAS Number

133-06-2

Formula

C9-H8-Cl3-N-O2-S

Major Category

Pesticides

Synonyms

N-Trichloromethylthio-4-cyclohexane-1,2-dicarboximide; Vancide 89; Dangard; Merpan; Orthocide-406; SR-406; [Marks, p. 268] Agrox; Captal; Captec; Captol; Captonex; Clomitane; Merpan; Meteoro; Orthocide; Phytocape; Sepicap; Sorene; Vancide 89; [EXTOXNET]

Category

Fungicides

Description

Odorless, white, crystalline powder. [fungicide] [Note: Commercial product is a yellow powder with a pungent odor.]; [NIOSH]

Sources/Uses

The thiophthalimides are widely used fungicides on seeds, field crops, and stored produce; [EPA Pesticides] Captan is also used as a biocide in paints, polishes, shampoos, and cosmetics. [Kanerva, p. 1765] No longer used as a fungicide in hair-care products; [Kanerva, p. 1516]

Comments

The thiophthalimides include captan, captafol and folpet; no systemic poisonings in humans have been reported; [EPA Pesticides] Captan is an agricultural fungicide that has caused occupational allergic contact dermatitis usually after airborne exposure. [Marks, p. 267] Allergic contact dermatitis also reported in hairdressers, painters, polishers, and varnishers; [Kanerva, p. 1765] In high-dose reproductive animal studies, captan causes testicular damage and fetal losses. It is a possible teratogen. [Frazier, p. 232-4] Not teratogenic in rats; Teratogenic in hamsters at a single dose of >750 mg/kg on day 7 or 8 of gestation; [ACGIH]

Restricted

Most uses on food crops were cancelled by the EPA in 1989 [EXTOXNET]

Reference Link

EXTOXNET - Captan

Exposure Assessment
Skin Designation (ACGIH)

No

TLV (ACGIH)

5 mg/m3, inhalable particulate matter

Reference Link

ICSC: Captan

Adverse Effects
Skin Sensitizer

Yes

Reproductive Toxin

Yes

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: