Agent Name

Carbon tetrabromide

Alternative Name

Tetrabromomethane

CAS Number

558-13-4

Formula

C-Br4

Major Category

Solvents

Synonyms

Carbon bromide; Methane tetrabromide; Tetrabromomethane; [NIOSH] UN2516

Category

Brominated Solvents

Description

Colorless to yellow-brown crystals with a slight odor; [NIOSH]

Sources/Uses

Used in organic syntheses; [ACGIH]

Comments

In an acute study of mice, carbon tetrabromide was determined to be 2.2 times more toxic to the liver than carbon tetrachloride. It causes significant eye irritation (tearing) in workers even at lower exposure levels. [ACGIH] A lachrymator; [HSDB] Inhalation of high concentrations can cause CNS depression; Causes corrosive burns to eyes [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.1 ppm

STEL (ACGIH)

0.3 ppm

Vapor Pressure

0.72 mm Hg

Half Life

For bromide (depends on compound and route of administration) whole body: 1 hour to 12 days; [TDR, p. 214]

Adverse Effects
Lacrimator

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Primary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: