Agent Name

3-Nitropropionic acid

CAS Number

504-88-1

Formula

C3-H5-N-O4

Major Category

Biological Agents

Synonyms

3-Nitropropanoic acid; BNP; Bovinocidin; Hiptagenic acid; NITROPROPIONIC ACID, BETA; Propanoic acid, 3-nitro-; Propionic acid, 3-nitro-; beta-Nitropropionic acid; [ChemIDplus] UN2811

Category

Mycotoxins

Description

Golden solid; [CAMEO] Fine faintly beige crystals; [MSDSonline]

Sources/Uses

A naturally occurring mycotoxin that is associated with motor disorders in livestock and humans that have ingested contaminated food; Used as a research chemical; Not commercially produced in the US; [HSDB]

Comments

Emergency treatment: Methemoglobinemia; Thought to be the cause of acute mildewed sugar cane poisoning; There were 88 deaths in China attributed to this mycotoxin between 1972 and 1989; [HSDB] Causes somnolence and seizures in intraperitoneal, lethal-dose studies of rats; LDLo (rabbits) = 355 mg/kg; Has effect on neurotransmitters (putative); [RTECS] A skin, eye, mucous membrane, and upper respiratory tract irritant; [CAMEO] An irritant; [MSDSonline]

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.