Agent Name

p-Aminosalicylic acid

CAS Number

65-49-6

Formula

C7-H7-N-O3

Major Category

Nitrogen Compounds

Synonyms

2-Hydroxy-4-aminobenzoic acid; 3-Hydroxy-4-carboxyaniline; 4-Amino-2-hydroxybenzoic acid; 4-Aminosalicylic acid; A 1909; APAS; Aminopar; Aminosalicylic acid; Aminosalyl; Aminox; Apacil; Benzoic acid, 4-amino-2-hydroxy-; Deapasil; Entepas; Ferrosan; Gabbropas; Helipidyl; Hellipidyl; Kyselina p-aminosalicylova [Czech]; NIH 2939; Osacyl; PAS; PAS (VAN); PAS (acid); PAS-C; Pamacyl; Pamisyl; Para-Pas; Para-amino salicylic acid; Paramycin; Parasal; Parasalicil; Parasalindon; Pas; Pasa; Pasalon; Pasara; Pascorbic; Pasdium; Pasem; Paser; Paser Granules; Pask; Pasmed; Pasnodia; Pasolac; Propasa; Rezipas; Salicylic acid, 4-amino-; Sanipirol-4; [ChemIDplus]

Category

Aminobenzoic Acids

Description

White or nearly white solid; Affected by light and air; [Hawley] Beige powder; [MSDSonline]

Sources/Uses

Used as an industrial preservative, a chemical intermediate, and an antitubercular drug; [HSDB]

Comments

Not expected to increase congenital malformations based on animal studies; [REPROTOX] Oral LD50 (mouse) = 4000 mg/kg; [RTECS] An eye irritant; Targets the GI system and liver; [MSDSonline] See "p-Aminosalicylic acid sodium salt dihydrate."

Exposure Assessment
Vapor Pressure

4.0E-6 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.