Disease/Syndrome

Asphyxiation, chemical

Category

Acute Poisoning

Acute/Chronic

Acute-Severe

Synonyms

Toxic asphyxiation

Biomedical References

Search PubMed

Comments

Chemical asphyxiants include hydrogen cyanide (HCN), hydrogen sulfide (H2S), and carbon monoxide (CO). HCN and H2S combine with enzymes to disrupt respiration at the cellular level, while CO binds with hemoglobin to block the delivery of oxygen to the cells. Other findings may include confusion, ataxia, weakness, and tachycardia that can progress to bradycardia and asystole. [5MCC, Current Consult, p. 1078, 1091, Ford, p. 706]

Latency/Incubation

Seconds to hours

Diagnostic

History; signs of brain hypoxia; carboxyhemoglobin level;

ICD-9 Code

986

Related Information in Haz-Map
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Job Tasks

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Agents

Hazardous agents that cause the occupational disease: