Agent Name

Agaritine

CAS Number

2757-90-6

Formula

C12-H17-N3-O4

Major Category

Biological Agents

Synonyms

Glutamic acid, 5-(2-(alpha-hydroxy-p-tolyl)hydrazide), L-; L-Glutamic acid, 5-(2-(4-(hydroxymethyl)phenyl)hydrazide); L-Glutamic acid, 5-(2-(alpha-hydroxy-para-tolyl)hydrazide); beta-N-(gamma-L(+)Glutamyl)4-hydroxymethylphenylhydrazine; beta-N-(alpha-L-Glutamyl)-4-hydroxymethylphenylhydrazine; [ChemIDplus]

Category

Mushroom Toxins

Description

Solid; [Merck Index]

Sources/Uses

Natural substance in several mushrooms in the Agaricus species, consumed both raw and cooked throughout the world; [IARC] A natural and edible constituent of commercial mushrooms; [Merck Index]

Comments

Adverse effects to mice after single injections of up to 400 mg/kg were excitation, seizures, and paralysis with histopathological evidence of injury to the liver, kidneys, bladder and lungs;; No data in humans; Inadequate evidence of carcinogenicity in animals; [IARC] Highly toxic; [CAMEO]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Other Information

No other related information on this agent was found.