Agent Name

Aldicarb oxime

CAS Number

1646-75-9

Formula

C5-H11-N-O-S

Major Category

Nitrogen Compounds

Synonyms

2-(Methylthio)-2-methylpropionaldehyde oxime; 2-(Methylthio)isobutyraldehyde oxime; 2-Methyl-2-(methylthio)propanal oxime; 2-Methyl-2-(methylthio)propionaldehyde oxime; 2-Methyl-2-(methylthio)propionaldoxime; Propanal, 2-methyl-2-(methylthio)-, oxime; Propionaldehyde, 2-methyl-2-(methylthio)-, oxime; Temik oxime; [ChemIDplus]

Category

Oximes

Description

Colorless, viscous liquid with an unpleasant sulfurous or musty odor; [CAMEO]

Sources/Uses

Used to make Aldicarb (insecticide); [HSDB]

Comments

Gavage doses above 20 mg/kg cause marked CNS effects and death in female mice; Doses up to 15 mg/kg/day caused no adverse clinical, gross, histopathological, or immunological changes to female mice in 14 day consecutive gavage study; [HSDB] May form hazardous peroxides; Sensitive to heat and may decompose on prolonged contact with moisture; A skin, eye, and respiratory tract irritant; May cause corneal damage, CNS effects, and kidney and hematological disorders; [CAMEO] Moderately irritating to rabbit skin and corrosive to rabbit eyes; No mortality or adverse clinical, hematological, gross, or histopathological changes observed besides reduced body weights in females at highest dose (120 mg/kg/day) in 13-week feeding study of rats; [EPA HPVIS]

Exposure Assessment
Lethal Concentration

LC50 (rat) = 1,230 mg/m3/4h

Explanatory Notes

Flash point = 118 deg C; VP <0.1 mm Hg at20 deg C; [CAMEO]

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Other Information

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