Agent Name

Chlorobromomethane

Alternative Name

Bromochloromethane

CAS Number

74-97-5

Formula

C-H2-Br-Cl

Major Category

Solvents

Synonyms

Bromochloromethane; Chloromethyl bromide; Fluorocarbon 1011; Halon 1011; Methane, bromochloro-; Methylene chlorobromide; Mil-B-4394-B; Mono-chloro-mono-bromo-methane; [ChemIDplus] UN1887

Category

Chlorofluorocarbons

Description

Colorless to pale-yellow liquid with a chloroform-like odo; Note: May be used as a fire extinguishing agen; [NIOSH]

Sources/Uses

Used in fire extinguishers; [ACGIH]

Comments

In animal studies, causes reversible liver injury, narcosis, and anesthesia; Fire fighters exposed to high concentrations lost consciousness. [ACGIH]

Restricted

See CHLOROFLUOROCARBONS

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

200 ppm

PEL (OSHA)

200 ppm

IDLH (NIOSH)

2000 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: Patty [1963] reported that light narcosis could be produced in animals at 3,000 ppm, and pulmonary edema and deaths during exposure at 27,000 ppm; delayed deaths occurred after exposure to 20,000 ppm [Comstock et al. 1953]. Patty [1963] also reported that guinea pigs survived 1hour exposures but 1 of 3 guinea pigs died after 2hour exposures to 8,000 to 10,000 ppm [Matson and Dufour 1948]. . . . Basis for revised IDLH: The revised IDLH for chlorobromomethane is 2,000 ppm based on acute inhalation toxicity data in animals [Comstock et al. 1952; Comstock and Oberst 1953; Matson and Dufour 1948]. This may be a conservative value due to the lack of relevant acute toxicity data for workers.

Vapor Pressure

142 mm Hg

Odor Threshold Low

397 ppm

Lethal Concentration

LCLo (rat) = 28,800 ppm/15 min

Explanatory Notes

Odor threshold from ACGIH;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: