Agent Name

Chloromethyl methyl ether

Alternative Name

Monochlorodimethyl ether

CAS Number

107-30-2

Formula

C2-H5-Cl-O

Major Category

Other Classes

Synonyms

Monochlorodimethyl ether; Chlordimethylether [Czech]; Chlorodimethyl ether; Chloromethoxymethane; Chloromethyl methyl ether; Dimethylchloroether; Ether methylique monochlore [French]; Ether, chloromethyl methyl; Ether, dimethyl chloro; Methane, chloromethoxy-; Methoxychloromethane; Methoxymethyl chloride; Methylchloromethyl ether; Monochlorodimethyl ether; Monochloromethyl methyl ether; alpha,alpha-Dichlorodimethyl ether; [ChemIDplus] Methyl chloromethyl ether; UN1239; [ERG 2012]

Category

Halogenated Ethers

Description

Colorless liquid with an irritating odor; [NIOSH]

Sources/Uses

Used as a methylating agent; [ACGIH]

Comments

Liquid causes second degree burns after contact for a few minutes; [CHRIS] CMME becomes rapidly contaminated with bis-chloromethyl ether, a known human carcinogen; [ACGIH] A lachrymator; [HSDB] A corrosive substance that can cause pulmonary edema; [ICSC]

Restricted

Carcinogen--see 29 CFR 1910.1003;

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

Vapor Pressure

30 mm Hg

Lethal Concentration

LC50 (rat) = 55 ppm/7h

Explanatory Notes

Carcinogen--No TLV; Flash point = 0 deg C;

Half Life

No reports found; [TDR, p. 851]

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Suspected Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: