Agent Name

Amanin

CAS Number

21150-21-0

Formula

C39-H53-N9-O14-S

Major Category

Biological Agents

Synonyms

9,18- (Iminoethaniminoethaniminoethaniminomethano)pyrrolo(1',2':8, 9)(1,5,8,11,14)thiatetraaza cyclooctadecino(18,17-b)indole- 6-acetic acid, 1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-29-sec-butyl-21-(2,3-dihydroxy-1-methylpropyl)-2-hydroxy-5,8,20,23,24,27,30,33-octaoxo-, 11-oxide; Amanine; alpha-Amanitin, 1-L-aspartic acid-4-(2-mercapto-L-tryptophan)-; [ChemIDplus]

Category

Mushroom Toxins

Sources/Uses

Amanitin toxins from the poisonous Amanita phalloides mushroom include amanin. [Merck Index]

Comments

Inhibits protein synthesis in mammalian cells; [Merck Index] Emergency treatment: "Mushrooms- cyclopeptides"; [HSDB] Oral LD50 (mammal) = 0.5 mg/kg; [RTECS] See "alpha-Amanitin" and "beta-Amanitin."

Reference Link

INCHEM: Management of Poisoning by Unknown Fungi

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.